Polyethylenimine-based intravenous delivery of transgenes to mouse lung
نویسندگان
چکیده
منابع مشابه
Polyethylenimine-mediated gene delivery to the lung and therapeutic applications
Nonviral gene delivery is now considered a promising alternative to viral vectors. Among nonviral gene delivery agents, polyethylenimine (PEI) has emerged as a potent candidate for gene delivery to the lung. PEI has some advantages over other polycations in that it combines strong DNA compaction capacity with an intrinsic endosomolytic activity. However, intracellular (mainly the nuclear membra...
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ژورنال
عنوان ژورنال: Gene Therapy
سال: 1998
ISSN: 0969-7128,1476-5462
DOI: 10.1038/sj.gt.3300717